ImmunologybioRxivPreprint
SATB1 maintains naive-like identity in antiviral CD8⁺ T cells by limiting chromatin remodelling at effector gene loci.
Jason K.C. Lee, Adele A. Barugahare, Ioanna Gemund…·Stephen T. Turner
This study identifies SATB1 as a regulator that maintains naive CD8+ T cell identity by restricting chromatin remodelling at effector gene loci, preventing premature differentiation during viral infection.