David R. Boyer

The paper shows a D-peptide disassembles AD-tau fibrils via a strain-relief mechanism involving oppositely twisted fibrils.

The paper uses cryo-electron microscopy to show that cardiac ATTR amyloid fibrils are structurally polymorphic, independent of genotype and phenotype, challenging the one-fibril-fold-per-disease paradigm.

This paper presents the cryoEM structure of hnRNPA2 LCD fibrils, showing structural differences from pathogenic amyloid and how mutations convert it to a pathogenic form.