Molecular BiologybioRxivPreprint
Intra-host IRES heterogeneity shapes hepatitis C virus translation through epistatic and population-level effects
Natalia Echeverría, Paula Perbolianachis, Fabiana Gámbaro…·Gonzalo Moratorio
This study shows that natural variation in HCV IRES affects translation efficiency through epistasis and population-level effects, challenging reliance on dominant sequences.
DOI 10.64898/2026.08.05.743084