Cancer BiologyBMC CancerPeer-reviewed
A genetically encoded fluorescent sensor enables sensitive and specific detection of IDH mutant associated oncometabolite D-2-hydroxyglutarate
Kristian A. Choate, W. W. L. Konickson, Zoe Moreno…·Evan P.S. Pratt
This paper develops a genetically encoded fluorescent sensor, D2HGlo, for detecting D-2-HG, an oncometabolite associated with IDH mutations, and demonstrates its utility in diagnosing IDH mutant cancers.
4 citations