Author

Emma L. Hesketh

University of LeedsORCID 0000-0002-4522-0061Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:cryo-EM· 2 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Approach:microscopy & imaging analysis· 1 Research Focus:protein folding & dynamics· 1 Organism:virus· 1

Frequent Co-Authors

Asger Meldgaard FrankiD· 1 shared Claudia LanceyiD· 1 shared Cuifeng YingiD· 1 shared David M. LawsoniD· 1 shared Francisco OlmoiD· 1 shared George P. LomonossoffiD· 1 shared Ivan CampeottoiD· 1 shared John E. JohnsoniD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperBiophysics

Asger Meldgaard FrankORCID

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2 papers

Recent·Most cited

BiochemistryProceedings of the National Academy of SciencesPeer-reviewedFeb 25, 2026

Unravelling the Maturation Pathway of a Eukaryotic Virus through Cryo-EM

Roger Castells‐Graells, Emma L. Hesketh, Tsutomu Matsui…·George P. Lomonossoff

This study uses cryo-EM to determine structural models of five intermediates in the maturation pathway of Nudaurelia capensis omega virus, revealing key structural changes during viral maturation.

DOI 10.1073/pnas.2420493123

viruscryo-EM

BiophysicsNature CommunicationsPeer-reviewedAug 5, 2025

Cryo-EM led analysis of open and closed conformations of Chagas vaccine candidate TcPOP and its antibody response characterisation

Sagar Batra, Francisco Olmo, Timothy J. Ragan…·Ivan Campeotto

This study determines the 3D structures of TcPOP in open and closed conformations using cryo-EM and evaluates its immunogenicity through antibody responses in mice.

2 citations

cryo-EMexperimental assay