Author

Rachel D. Crouch

Lipscomb UniversityORCID 0000-0002-4525-6072Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:perturbation response prediction· 1 Research Focus:phylogenetics / evolution· 1 Organism:rat· 1

Frequent Co-Authors

Abigail N. SmithiD· 1 shared Björn C. KnollmanniD· 1 shared Jeffrey N. JohnstoniD· 1 shared Kevin WuiD· 1 shared Madelaine P. ThorpeiD· 1 shared Tri Q. DoiD· 1 shared Wendell S. Akers· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

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1 shared paperPharmacology & Toxicology

Abigail N. SmithORCID

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1 paper

Recent·Most cited

Characterization of the Preclinical in Vitro and in Vivo Pharmacokinetic Properties of the Cyclic Oligomeric Depsipeptide Ryanodine Receptor 2 Inhibitor ent-Verticilide

Tri Q. Do, Rachel D. Crouch, Kevin Wu, Madelaine P. Thorpe, Abigail N. Smith, Jeffrey N. Johnston, Wendell S. Akers, Björn C. Knollmann

This study characterizes the pharmacokinetic properties of ent-verticilide, identifying limited intestinal availability and CYP-mediated metabolism as key factors affecting its oral exposure.

bioRxiv · Oct 27, 2026 · PreprintPharmacology & Toxicology