Reversion of a RND transporter pseudogene uncovers latent stress resistance in Brucella ovis
Thomas Kim, Bongjin Hong, Thomas V. O’Halloran, Erika Mathes Lisabeth, Richard R. Neubig, Aretha Fiebig, Sean Crosson
This study identifies dihydropyridines as inhibitors of Brucella ovis growth and shows that pseudogenes like bepE can confer stress resistance through functional restoration.
bioRxiv · May 10, 2025 · PreprintMicrobiology