Author

Sergio Pirola

Centro Cardiologico MonzinoORCID 0000-0002-4573-8346Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Albino CarrizzoiD· 1 shared Alice BonomiiD· 1 shared Antoine RimbertiD· 1 shared Donato De Giorgi· 1 shared Francesca Bertolini· 1 shared Ilaria MassaiuiD· 1 shared Marco ZanobiniiD· 1 shared Matteo FranchiiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCell Biology

Albino CarrizzoORCID

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1 paper

Recent·Most cited

Sirtuin 1 modulation unlocks the therapeutic potential of sodium-glucose co-transporter 2 inhibitors (SGLT2i) in calcific aortic valve stenosis

Vincenza Valerio, Ilaria Massaiu, Matteo Franchi, Antoine Rimbert, Zoé Begué-Racapé, Mattia Chiesa, Veronika A. Myasoedova, Valentina Rusconi, Francesca Bertolini, Donato De Giorgi, Alice Bonomi, Sergio Pirola, Marco Zanobini, Paola Di Pietro, Albino Carrizzo, , Paolo Poggio

This study shows SIRT1 regulates calcific aortic valve stenosis progression and that SGLT2i may slow valve degeneration by modulating SIRT1.

Cardiovascular Research · Sep 5, 2026Peer-reviewedCell Biology