Author

Q Y Zhang

Xijing HospitalORCID 0000-0002-4583-6552Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:benchmarking· 1 Research Focus:database / resource· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Fei Tian· 1 shared Hong-Mei ZhangiD· 1 shared Hongchen JiiD· 1 shared Jianwei Wu· 1 shared Jiawei Chang· 1 shared Mengdi Zheng· 1 shared X. M. Li· 1 shared Xiangxu WangiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperGenetics

Fei Tian

Mutual co-authors in cluster

Author profile →

1 paper

Recent·Most cited

Structural semantic evolutionary distance (SSED) unifies the selection of cancer driver genes across macroevolution and tumorigenesis.

Hongchen Ji, Q Y Zhang, Jianwei Wu, Fei Tian, Xiangxu Wang, Xiao Chai, Jiawei Chang, Mengdi Zheng, X. M. Li, Hong-Mei Zhang

This paper introduces SSED, a metric using ESM-3 to quantify evolutionary divergence, showing cancer driver genes are structurally constrained and that oncogenic mutations follow similar principles, predicting immune response.

bioRxiv · Dec 19, 2025 · PreprintGenetics