Author

Xiangxu Wang

Xijing HospitalORCID 0000-0003-4084-7866Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Research Focus:database / resource· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Fei Tian· 1 shared Hong-Mei ZhangiD· 1 shared Hongchen JiiD· 1 shared Jianwei Wu· 1 shared Jiawei Chang· 1 shared Mengdi Zheng· 1 shared Q Y ZhangiD· 1 shared X. M. Li· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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9 top collaborators · 36 mutual co-author links

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1 shared paperGenetics

Fei Tian

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1 paper

Recent·Most cited

GeneticsbioRxivPreprintDec 19, 2025

Structural semantic evolutionary distance (SSED) unifies the selection of cancer driver genes across macroevolution and tumorigenesis.

Hongchen Ji, Q Y Zhang, Jianwei Wu…·Hong-Mei Zhang

This paper introduces SSED, a metric using ESM-3 to quantify evolutionary divergence, showing cancer driver genes are structurally constrained and that oncogenic mutations follow similar principles, predicting immune response.

DOI 10.64898/2025.12.17.694808

humanproteomics

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