MORPHIS (MORPHological Interpretable Signature) captures heterogeneous treatment- and aging-related responses of single cells
Freja Bohr, Athanasios Oikonomou, Emilie Milan Nielsen, Georgios Konstantinidis, Janni Støvring Mortensen, Nektarios Tavernarakis, Hanne Mørck Nielsen, Nikos S. Hatzakis
MORPHIS quantifies single-cell morphological responses to treatments and aging, distinguishing compound-specific signatures and aging-related changes in Caco-2, HeLa, and C. elegans cells.
bioRxiv · Mar 25, 2026 · PreprintBiophysics