Author

Sohini Chakraborti

University of DundeeORCID 0000-0002-4591-2658Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:biophysical modeling· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:structural biology· 1

Frequent Co-Authors

Alessio CiulliiD· 1 shared Angus D. CowaniD· 1 shared Denis SchmidtiD· 1 shared Elisha H. McCroryiD· 1 shared Elizabeth K. J. HoggiD· 1 shared Florian P. C. BinderiD· 1 shared Giacomo PadroniiD· 1 shared Giorgia KiddiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

Alessio CiulliORCID

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1 paper

Recent·Most cited

Tuning the open-close equilibrium of Cereblon with small molecules influences protein degradation

Suzanne O’Connor, Zoe J. Rutter, Angus D. Cowan, Markus Zeeb, Florian P. C. Binder, Yuting Cao, Sohini Chakraborti, Stefan Djukic, Leonhard Geist, Elizabeth K. J. Hogg, Giorgia Kidd, Matthias Krumb, Simon Langer, Denis Schmidt, Liam Martin, , Alessio Ciulli

This study identifies CRBN binders that induce or fail to induce CRBN closure, showing that closure is critical for degrader activity.

bioRxiv · Dec 22, 2025 · PreprintBiochemistry