Janetta Top

This study evaluates the effectiveness of Oxford Nanopore adaptive sampling in metagenomic profiling of clinical sputum samples, finding limited enrichment and significant pore loss issues.

The paper introduces LDWeaver, a method to detect co-selection in bacterial genomes by analyzing both short- and long-range linkage disequilibrium, and validates findings using functional annotation and phenotypic measurements.

This study shows that dietary cystine restriction in mice increases small intestine proliferation but not systemic effects or colon mucus barrier integrity.

This study quantifies the modes of vanA-type vancomycin resistance dissemination in Dutch hospitals, finding clonal spread as the dominant mechanism with significant contributions from horizontal gene transfer.

This paper uses genome-wide co-evolution analysis to identify genomic rearrangements in Enterococcus faecium, linking them to adaptation to hospital environments.

This study analyzes the genomes of Enterococcus faecium strains to understand their adaptive evolution, identifying plasmids as key indicators of host specificity through population-wide genomic analysis.