Alan McNally

This study shows that library preparation methods significantly affect RNA virus detection in clinical metagenomics, with SISPA-based approaches outperforming others in most scenarios.

This study analyzes the capsule operon genetics of E. coli ST131 using 3,033 genomes, identifying a monophyletic group with divergent kpsM and kpsT genes linked to host-pathogen interactions.

The paper identifies a seventh RND efflux pump, EefABC, in E. coli phylogroups associated with infection, showing high conservation and distinct structural features compared to known systems.

The paper shows that exposure to pyocyanin from Pseudomonas aeruginosa increases antibiotic resistance evolution in enterococci through efflux mechanisms.

This study shows glucose reduces gentamicin efficacy against UPEC and influences mutation acquisition during antibiotic exposure.

This study uses genomic sequencing to show low levels of multi-drug resistant E. coli in a UK ICU during strict COVID-19 measures, with only one carbapenemase-producing strain identified.

The paper identifies a plasmid lineage pQEB1 carrying blaKPC-2 in a hospital outbreak, showing its multi-drug resistance and inter-patient transmission.

This study analyzes the genomes of Enterococcus faecium strains to understand their adaptive evolution, identifying plasmids as key indicators of host specificity through population-wide genomic analysis.

This study identifies negative frequency-dependent selection in Escherichia coli ST131 as a key driver of its evolutionary success and adaptation to different ecological niches.