Edwin C.A. Stigter

The paper uses single-cell proteomics to show that GFAP mutations in Alexander disease lead to ETC dysfunction and metabolic adaptation via the G3P shuttle.

This study shows that localized hydrogen peroxide production induces p53-dependent resistance to DNA damage, with implications for chemotherapy protection.

The paper develops a metabolite signature to predict post-weaning diarrhoea in pigs using mass spectrometry and machine learning, but finds no consistent pathway enrichment.

This study shows that glycolytic reprogramming in JIA CD4+ T cells drives epigenetic changes linked to inflammation, with potential therapeutic implications.

This study shows that dietary cystine restriction in mice increases small intestine proliferation but not systemic effects or colon mucus barrier integrity.