Sila Genc

TRAMFIX evaluates the reproducibility of fixel-based analysis across multiple MRI scanners and finds high reliability for whole-brain and tract-level metrics, with some variability at the fixel level.

The paper uses MRI to show age-related changes in cortical microstructure that align with oligodendrocyte gene expression during development.

This study investigates age-related changes in hippocampal microstructure using diffusion MRI in children and adolescents, finding significant developmental changes in neurites, soma, and mean diffusivity.

This study examines age-related changes in microstructure-informed cortical networks using diffusion MRI data from 8-18 year olds, finding increased global efficiency and mean strength in specific networks.

This paper introduces a weighted generative model of the human connectome that captures both topology and edge-weights, showing improved accuracy over previous models.

This paper develops a surface-based tractography method for short association fibres in the human brain, showing it produces longer streamlines and high cortical coverage but with limited reliability and repeatability.

This study evaluates variability in white matter bundle segmentation across 42 groups using the same dataset, finding protocol variability exceeds other sources of inconsistency.

This study assesses the repeatability of soma and neurite metrics in grey matter using diffusion MRI across five scans of six healthy adults, finding high reliability in key measures.

This study finds that childhood conduct problems are associated with reduced white matter fibre density and morphology in specific brain pathways.

This study examines white matter development in children aged 9-13, finding increases in fibre density linked to puberty, attentional difficulties, and mental health issues.

This study examines how different b-value settings affect apparent fibre density estimates in diffusion MRI, finding that higher b-values improve accuracy in capturing intra-axonal signal properties and age-related microstructural changes.

This paper reduces the dimensionality of diffusion MRI measures to identify biologically interpretable components that capture age-related changes in white matter microstructure.

This study uses longitudinal fixel-based analysis to show increased white matter fibre density and cross-section in specific brain regions over 16 months, with no significant effect of pubertal stage.

The paper examines age, sex, and puberty effects on corpus callosum development using diffusion MRI metrics across multiple regions.