Timothy J. Silk

The paper identifies genetic and environmental factors influencing DNA methylation in ADHD and controls across childhood, showing income and school quality affect methylation changes differently by ADHD trajectory.

The paper applies an existing brain-age model to longitudinal adolescent MRI data, finding moderate consistency but issues with accuracy and age-related bias.

The paper examines brain-age gaps in adolescents with different mental health profiles, finding higher brain-age in those with moderate distress and lower suicidal ideation.

Across 15 cohorts (birth to 24 years), 20 epigenetic clocks and eight brain age models predicted chronological age modestly, stabilizing by middle childhood; their age residuals were weakly associated.

This study finds no group differences in sustained attention performance or wake slow wave activity between ADHD and neurotypical adults, but identifies neural differences suggesting compensatory mechanisms in ADHD.

This study finds that increased sleep-like slow wave (SW) density during wakefulness in ADHD is associated with attentional difficulties, suggesting a mechanistic link between sleep disturbances and attentional issues.

This study uses diffusion MRI to examine limbic system white matter development in children and adolescents with ADHD, finding reduced microstructural organization and connectivity linked to symptom severity.

The paper examines how earlier pubertal timing affects mental health through changes in corticolimbic connectivity in adolescents, finding mediation effects on withdrawn depressed problems and environmental moderation.

The paper uses MVPA to compare neural profiles of frontoparietal networks in boys with ADHD, PDD, and TD, finding differences in working memory processing.

This study analyzes structural brain asymmetries in ADHD using 39 datasets, finding small effects that do not meet study-wide significance thresholds.

This study uses machine learning to show that structural brain anomalies in ADHD are similar in children and adults, supporting continuity of the disorder's pathophysiology.

This study examines how pubertal tempo affects cortical development trajectories in adolescents using longitudinal MRI data.

This study finds that childhood conduct problems are associated with reduced white matter fibre density and morphology in specific brain pathways.

This study examines white matter development in children aged 9-13, finding increases in fibre density linked to puberty, attentional difficulties, and mental health issues.

This study uses longitudinal fixel-based analysis to show increased white matter fibre density and cross-section in specific brain regions over 16 months, with no significant effect of pubertal stage.

The paper examines age, sex, and puberty effects on corpus callosum development using diffusion MRI metrics across multiple regions.