Greg D. Parker

Tract-specific white matter microstructure alterations among young adult APOE ε4 carriers: A replication and extension study

This study replicates and extends previous findings on white matter microstructure in young APOE ε4 carriers, finding no PHCB differences but altered ILF asymmetry.

Surface-based tracking for short association fibre tractography

This paper develops a surface-based tractography method for short association fibres in the human brain, showing it produces longer streamlines and high cortical coverage but with limited reliability and repeatability.

Mutation-related apparent myelin, not axon density, drives white matter differences in premanifest Huntington's disease: Evidence from in vivo ultra-strong gradient MRI

This study uses ultra-strong gradient MRI to show that myelin changes, not axon density, are linked to premanifest Huntington's disease, with mutation size correlating with myelin levels.

Distributional changes in myelin-specific MRI markers uncover dynamics in the fornix following spatial navigation training

This study uses multiple MRI techniques to analyze microstructural changes in white matter tracts after spatial navigation training in rats, finding significant distributional changes in myelin-specific measures.

Drumming motor sequence training induces myelin remodelling in Huntington's disease: a longitudinal diffusion MRI and quantitative magnetization transfer study

This study examines if drumming training induces myelin remodelling in Huntington's disease patients using diffusion MRI and qMT imaging, finding increased MPF in specific white matter regions post-training.

Impact of b-value on estimates of apparent fibre density

This study examines how different b-value settings affect apparent fibre density estimates in diffusion MRI, finding that higher b-values improve accuracy in capturing intra-axonal signal properties and age-related microstructural changes.

Mapping axon conduction delays in vivo from microstructural MRI

This paper estimates axon conduction velocity in vivo from MRI parameters, showing that 89.2% of variance is explained by axon diameter and g-ratio, with accurate estimates achievable under certain parameter bounds.

Mammillothalamic disconnection alters hippocampo-cortical oscillatory activity and microstructure: Implications for diencephalic amnesia

This study investigates how damage to the mammillothalamic tract affects hippocampo-cortical oscillatory activity and microstructure, linking these changes to memory impairments.

Dimensionality Reduction of Diffusion MRI Measures for Improved Tractometry of the Human Brain

This paper reduces the dimensionality of diffusion MRI measures to identify biologically interpretable components that capture age-related changes in white matter microstructure.

Curious connections: white matter pathways supporting individual differences in epistemic and perceptual curiosity

The paper investigates how individual differences in epistemic and perceptual curiosity relate to white matter tract microstructure in specific brain networks.

Genetic risk for schizophrenia and developmental delay is associated with shape and microstructure of midline white matter structures

The paper investigates how genetic risk for schizophrenia and developmental delay relates to structural brain abnormalities in midline white matter.

Tractography in the presence of white matter lesions in multiple sclerosis

This study compares tractography algorithms in MS patients to assess their ability to segment white matter tracts despite lesions, showing that individual tract segmentation is feasible and reliable.