Author

David M. Walter

Broad InstituteORCID 0000-0002-4632-5113Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:spatial transcriptomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Akansha A. GuptaiD· 1 shared Anders B. DohlmaniD· 1 shared Daniel Denney· 1 shared Ethan Shurberg· 1 shared Garrett Michael FramptoniD· 1 shared Iris TIENLYNN. LeeiD· 1 shared Jakob M. Heinz· 1 shared Katherine Cho· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Akansha A. GuptaORCID

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1 paper

Recent·Most cited

U2AF1 mutations rescue deleterious exon skipping induced by KRAS mutations

David M. Walter, Katherine Cho, Smruthy Sivakumar, Daniel Denney, Iris TIENLYNN. Lee, Anders B. Dohlman, Jakob M. Heinz, Ethan Shurberg, Kevin X. Jiang, Akansha A. Gupta, Garrett Michael Frampton, Matthew M. Meyerson

This study shows that U2AF1 mutations can rescue exon skipping caused by KRAS mutations in lung adenocarcinoma, revealing a dynamic interplay between splicing factor and oncogenic mutations.

Nature Genetics · Jul 1, 2026Peer-reviewedCancer Biology