Immunocompetent murine models recapitulate the heterogeneous tumor immune microenvironment of human liposarcoma
Amanda M. Shafer, Emma Kenna, Lexi-Ann F. Golden, Ahmed M. Elhossiny, Kyle D. Perry, Jodi M. Wilkowski, Wei Yan, Brynn Kaczkofsky, Jake J. McGue, Scott C. Bresler, Adam Heath Courtney, Jessie M. Dalman, Craig J. Galbán, Wei Hong Jiang, Carlos E. Espinoza, , Christina Vadala Angeles
This study develops an immunocompetent mouse model of liposarcoma that recapitulates human tumor subtypes and immune features, enabling preclinical immunotherapy research.
Clinical Cancer Research · Sep 10, 2025Peer-reviewedCancer Biology