Author

Jake J. McGue

University of MichiganORCID 0000-0001-6131-7798Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell-cell communication· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

Timothy L. FrankeliD· 2 shared Aaron M. UdageriD· 1 shared Adam Heath CourtneyiD· 1 shared Ahmed M. ElhossinyiD· 1 shared Alex C. SoupiriD· 1 shared Allison Marie MayiD· 1 shared Amanda M. ShaferiD· 1 shared Andrzej Antoni DlugosziD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCancer Biology

Timothy L. FrankelORCID

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2 papers

Recent·Most cited

Cancer BiologyClinical Cancer ResearchPeer-reviewedSep 10, 2025

Immunocompetent murine models recapitulate the heterogeneous tumor immune microenvironment of human liposarcoma

Amanda M. Shafer, Emma Kenna, Lexi-Ann F. Golden…·Christina Vadala Angeles

This study develops an immunocompetent mouse model of liposarcoma that recapitulates human tumor subtypes and immune features, enabling preclinical immunotherapy research.

2 citations

mousebulk RNA-seq

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Cancer BiologybioRxivPreprintJun 12, 2025

Spatial analysis reveals a novel inflammatory tumor transition state which promotes a macrophage-driven induction of sarcomatoid renal cell carcinoma

Allison Marie May, Suguru Kadomoto, Claire Williams…·Evan T. Keller

The paper identifies a transcriptional transition state in ccRCC cells that drives sarcomatoid transformation and enhances immunotherapy response via macrophage and T-cell interactions.

1 citation

humanscRNA-seq

𝕏 PostBluesky