William Casazza

This study shows that region-specific gray matter myelin changes in rats and humans correlate with stress-induced behavioral differences, suggesting a common mechanism across species.

CEWAS improves gene detection from GWAS by modeling cascading epigenomic and transcriptomic effects, identifying disease-related genes and novel biological processes.

The paper evaluates methods for estimating cell-type proportions in brain tissue using paired transcriptomic and immunohistochemistry data, showing some algorithms provide accurate estimates.

The paper identifies novel modifier genes for Huntington disease by combining population-scale gene expression data with patient genomic data.