HRS dephosphorylation at membrane contact sites promotes sorting within multivesicular endosomes
Minoo Razi, Louise H. Wong, Douglas Grimes, Thomas Burgoyne, Pedro L. V. Fale, Ewan MacDonald, Emily R. Eden, Michael J. Clague, Sylvie Urbé, Clare E. Futter
The paper shows that HRS dephosphorylation at ER:MVE contacts promotes efficient ILV formation during MVE sorting.
bioRxiv · Mar 11, 2026 · PreprintCell Biology