Differential control of growth and identity by HNF4α isoforms in pancreatic ductal adenocarcinoma
Pengshu Fang, Emily R. Wilson, Sydney N. Larsen, Walter A. Orellana, Margaret A Hall, Chris Stubben, Acramul Haque Kabir, Kajsa E. Affolter, Richard A. Moffitt, Xiaoyang Zhang, Eric L. Snyder
This study investigates the differential roles of HNF4α isoforms P1 and P2 in PDAC growth and differentiation, finding P2 supports growth better than P1.
Molecular Cancer Research · Jul 16, 2025Peer-reviewedCancer Biology