Author

Seok Hee Lee

University of California, San FranciscoORCID 0000-0002-4656-1618Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 2

Signature Assays, Organisms & Methods

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Organism:mouse· 2 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Paolo F. RinaudoiD· 2 shared Andrew AlambaniD· 1 shared David Jimenez‐MoralesiD· 1 shared Mitchell P. Rosen· 1 shared Mustafa G. AydoganiD· 1 shared Philip J. MarshiD· 1 shared Rhodel K. Simbulan· 1 shared Xiaowei LiuiD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 18 mutual co-author links

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2 shared papersDevelopmental Biology

Paolo F. RinaudoORCID

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2 papers

Recent·Most cited

Self-reinforcing ROS-aneuploidy feedback loop shapes preimplantation development

Seok Hee Lee, Andrew Alamban, Rhodel K. Simbulan, Philip J. Marsh, Mitchell P. Rosen, Mustafa G. Aydogan, Paolo F. Rinaudo

The paper identifies a self-reinforcing ROS-aneuploidy feedback loop in preimplantation development, showing that oxidative stress can induce persistent chromosomal alterations.

bioRxiv · Jul 22, 2026 · PreprintDevelopmental Biology

Murine blastocysts generated by in vitro fertilization show increased Warburg metabolism and altered lactate production

Seok Hee Lee, Xiaowei Liu, David Jimenez‐Morales, Paolo F. Rinaudo

This study shows that IVF-generated murine blastocysts exhibit increased Warburg metabolism and altered lactate production compared to naturally conceived embryos.

eLife · Sep 15, 2022Peer-reviewedDevelopmental Biology