Engineering non-exponential proliferation in Escherichia coli using functionalized protein aggregates
Ronald Van Eyken, Dries Oome, Kevin Broux, Sam Jordens, Abram Aertsen
This paper describes a method to engineer Escherichia coli to exhibit linear proliferation by using protein aggregates that produce a conditionally essential metabolite.
Nature Communications · Feb 21, 2026Peer-reviewedSynthetic Biology