Author

Alicen Burns Spaulding

National Institutes of HealthORCID 0000-0002-4687-3259Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:host-pathogen & immune response· 3 Approach:experimental assay· 2 Organism:human· 2 Organism:mouse· 1 Assay:proteomics· 1 Organism:rat· 1 Assay:spatial transcriptomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Daniel C. DouekiD· 3 shared Leonid SerebryannyyiD· 3 shared Boyd L. YountiD· 2 shared Bridget L. MenaschéiD· 2 shared Craig B. WileniD· 2 shared Emma L. KeeleriD· 2 shared I‐Ting TengiD· 2 shared Nicholas CatanzaroiD· 2 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersMicrobiology

Daniel C. DouekORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Aminopeptidase N is a receptor for hedgehog merbecoviruses

Min Jin, Victoria A. Jefferson, Zhe Zhao, Nicholas Catanzaro, Luca De Sabato, Emma L. Keeler, Bridget L. Menasché, C E Hoffman, Boyd L. Yount, Anna Castelli, Ilaria Di Bartolo, Gabriele Vaccari, Tyler N. Starr, Stephanie N. Seifert, Adrian A. Castellanos, , Michael C. Letko

This study identifies Aminopeptidase N as the receptor for hedgehog merbecoviruses and shows restricted cross-species receptor use.

Nature Microbiology · Sep 16, 2026Peer-reviewedMicrobiology

Vaccine imprinting drives increased SARS-CoV-2 variant infection in children

Timothy S. Johnston, Rahul Subramanian, Wakinyan Benhamou, Emily Howerton, Robin Schlesinger, Stephen D. Schmidt, Rachel Kazmierski, Mike Castro, Bob C. Lin, Amy R. Henry, Sarah C. Smith, Jesmine Roberts-Torres, Farida Laboune, I‐Ting Teng, Shuishu Wang, , Daniel C. Douek

The paper shows that vaccine imprinting influences susceptibility to SARS-CoV-2 variants in children by linking immune history, antibody neutralization, and infection risk.

bioRxiv · Aug 17, 2026 · PreprintImmunology

HKU5 bat merbecoviruses use divergent mechanisms to engage bat and mink ACE2 as entry receptors

Mia Madel Alfajaro, Emma L. Keeler, Ning Li, Nicholas Catanzaro, I‐Ting Teng, Zhe Zhao, Michael W. Grunst, Boyd L. Yount, Alexandra Schäfer, Danyi Wang, Arthur S. Kim, Aleksandra Synowiec, Mario A. Peña-Hernández, Ridwan Arinola, Ramandeep Kaur, , Craig B. Wilen

This study identifies bat and mink ACE2 as receptors for HKU5 merbecovirus, revealing distinct receptor interactions and highlighting mustelids as potential intermediate hosts.

bioRxiv · Feb 12, 2025 · PreprintMicrobiology