I‐Ting Teng

Co-administration of intranasal parainfluenza virus vaccines expressing antigenically distinct SARS-CoV-2 S antigens elicits broad and durable immunity in hamsters

This paper evaluates co-administration of two intranasal parainfluenza virus vectors expressing distinct SARS-CoV-2 S antigens in hamsters, showing broad and durable immunity against Omicron/BA.5 challenge.

Vaccine imprinting drives increased SARS-CoV-2 variant infection in children

The paper shows that vaccine imprinting influences susceptibility to SARS-CoV-2 variants in children by linking immune history, antibody neutralization, and infection risk.

Anti-Malaria Antibody Engineering Broadens Recognition Motifs and Reveals New Homotypic Interactions that Enhance Protective Breadth

This paper improves an anti-malaria antibody to broaden its recognition of malaria parasite proteins and enhances its protective effectiveness against diverse strains.

Protective immunity against malaria by a nanoparticle CIS43-based junctional vaccine alone or in combination with R21

This paper develops a nanoparticle-based junctional vaccine targeting PfCSP and compares its efficacy to the R21 vaccine in reducing malaria liver burden in mice.

Vaccine Elicitation of HIV-1 Neutralizing Antibodies Against Both V2 Apex and Fusion Peptide in Rhesus Macaques

This study designs a dual-epitope vaccine targeting HIV-1 Env's fusion peptide and V2 apex, showing it elicits neutralizing antibodies against both sites in rhesus macaques.

Transient glycan-shield reduction induces CD4-binding site broadly neutralizing antibodies in SHIV-infected macaques

This study shows that transient glycan deletions in SHIVs can induce CD4-binding site broadly neutralizing antibodies in macaques, offering a model for HIV vaccine design.

Intranasal parainfluenza virus-vectored vaccine expressing SARS-CoV-2 spike protein of Delta or Omicron B.1.1.529 induces mucosal and systemic immunity and protects hamsters against homologous and heterologous challenge

This study evaluates intranasal B/HPIV3 vaccines expressing SARS-CoV-2 spike proteins of different variants, showing they induce mucosal and systemic immunity and protect hamsters against homologous and heterologous challenges.

HKU5 bat merbecoviruses use divergent mechanisms to engage bat and mink ACE2 as entry receptors

This study identifies bat and mink ACE2 as receptors for HKU5 merbecovirus, revealing distinct receptor interactions and highlighting mustelids as potential intermediate hosts.