Chang‐Mei Liu

Roles of Kdm6a and Kdm6b in regulation of mammalian neural regeneration

This study investigates the roles of Kdm6a and Kdm6b in neural regeneration, finding they regulate axon regeneration and RGC survival with distinct mechanisms and identifying Klf4 as a downstream target.

MARK2 variants cause autism spectrum disorder via the downregulation of WNT/β-catenin signaling pathway

This study identifies MARK2 variants as a cause of autism spectrum disorder by showing they disrupt the WNT/β-catenin signaling pathway and impair neural development.

Histone methyltransferase Ezh2 coordinates mammalian axon regeneration via epigenetic regulation of key regenerative pathways

This study shows Ezh2 promotes axon regeneration in the PNS and CNS by epigenetically regulating genes involved in regeneration and inhibitory signaling.

Dynamic profiling and functional interpretation of histone lysine crotonylation and lactylation during neural development

The paper profiles histone lysine crotonylation and lactylation dynamics during neural development and identifies HDAC1-3 as novel erasers of H3K18la.

The Telomerase Reverse Transcriptase (TERT) and p53 Regulate Mammalian PNS and CNS Axon Regeneration downstream of c-Myc

The paper identifies TERT and p53 as regulators of axon regeneration downstream of c-Myc in the CNS and PNS, showing p53 overexpression promotes regeneration.

Calcium/calmodulin-dependent protein kinase II regulates mammalian axon growth by affecting F-actin length in growth cone

This study shows that CaMKII regulates axon growth by modulating F-actin length in growth cones, with implications for axon regeneration in both peripheral and central nervous systems.