Tuphan Kanti Dolai

CircNFATc3 promotes Fetal Hemoglobin induction by regulating let-7b/GATA2 axis

This study identifies circNFATc3 as a regulator of fetal hemoglobin induction through the let-7b/GATA2 axis, revealing its role in erythropoiesis and potential therapeutic applications for beta-thalassemia.

UCA1 lncRNA represses γ-globin expression by sequestering miR-148b, a key post-transcriptional regulator of BCL11A

The paper identifies UCA1 lncRNA as a ceRNA that sequesters miR-148b, increasing BCL11A expression and reducing γ-globin levels in adult erythroid cells.

Debunking the "junk": Unraveling the role of lncRNA-miRNA-mRNA networks in fetal hemoglobin regulation

The paper identifies lncRNA-miRNA-mRNA networks involved in fetal hemoglobin regulation using machine learning and public datasets.