Author

Paul A. Grimsrud

Duke UniversityORCID 0000-0002-4706-914XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:proteomics· 2

Frequent Co-Authors

Matthew D. HirscheyiD· 2 shared Akshay BarejaiD· 1 shared Beverly deSouza· 1 shared E. Keith KeenaniD· 1 shared Kristin A. Anderson· 1 shared Michael J. MuehlbaueriD· 1 shared Olga IlkayevaiD· 1 shared Pol Castellano‐EscuderiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersBiochemistry

Matthew D. HirscheyORCID

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2 papers

Recent·Most cited

Cysteine S-acetylation is a post-translational modification involved in metabolic regulation

E. Keith Keenan, Akshay Bareja, Yannie Lam, Paul A. Grimsrud, Matthew D. Hirschey

The paper identifies cysteine S-acetylation as a novel post-translational modification in mouse liver, revealing its cytoplasmic localization and tissue-specific patterns under metabolic stress.

npj Metabolic Health and Disease · Nov 7, 2025Peer-reviewedBiochemistry

SIRT4 Controls Macrophage Function and Wound Healing through Control of Protein Itaconylation in Mice

Kristin A. Anderson, Beverly deSouza, Pol Castellano‐Escuder, Zhihong Lin, Olga Ilkayeva, Michael J. Muehlbauer, Paul A. Grimsrud, Matthew D. Hirschey

This study identifies SIRT4 as a lysine deitaconylase that regulates macrophage inflammatory responses and wound healing by modulating protein itaconylation in mice.

bioRxiv · May 12, 2025 · PreprintMolecular Biology