Xingde D. Li

SPOTTER enables automated, high-plex spatial proteomics and phosphoproteomics by barcoding proteins on tissue sections, achieving deep coverage with LC-MS/MS.

This paper synthesizes pH-responsive nanocomposites using polymer-coated gold nanorods and demonstrates their optical property changes with pH.

This study compares physical and digital dispersion compensation in OCT, finding that digital methods can restore sensitivity but fail beyond a dispersion mismatch threshold.

This paper introduces a two-photon fiberscope with tunable focus for in vivo imaging at selected depths, demonstrating its performance using phantoms and biological samples.

This study introduces gold nanocages as scattering-dominant contrast agents for OCT, showing enhanced imaging contrast in tissue phantoms, ex vivo, and in vivo models.

This study develops gold nanocages with a surface plasmon resonance peak at 1060 nm as contrast agents for OCT imaging, showing enhanced imaging contrast in phantoms and mouse tissues.

This paper develops a method to correct multiple scattering in qOCT to improve tissue attenuation coefficient accuracy, validated with phantoms and simulations.

This paper demonstrates a Dove prism-based dual-fiberscope rotary joint for simultaneous two-photon imaging of two brain regions in freely-moving mice.