Julien Bryois

Genome-wide association meta-analysis of 130,664 major depression cases and 330,470 controls identifies 44 independent risk loci enriched in cortical neurons, conserved mammalian regions, splicing networks, and antidepressant targets.

The paper identifies brain cell types and genes associated with intelligence using GWAS and single-cell gene expression data from a large cohort.

This study identifies 9 novel genetic loci and 215 potential causative genes associated with Alzheimer's disease risk through a large genome-wide association analysis.

The paper uses Bayesian modeling to analyze rare exonic variants in schizophrenia and neurodevelopmental disorders, identifying 1,551 risk genes for schizophrenia and 98 new risk genes for developmental disorders.

The paper evaluates chromatin accessibility in prefrontal cortex samples from schizophrenia cases and controls, finding high heritability enrichment in open chromatin regions but no differential accessibility between groups.