Jingjing Zou

This study uses patient-derived organoids to identify CFTR modulators as a therapeutic strategy for chronic pancreatitis.

This study identifies CA19-9's role in remodeling the PDAC tumor microenvironment by inducing IL1a and TGFb, leading to immunosuppressive changes that can be mitigated by blocking these factors.

This study shows CA19-9 promotes pancreatic cancer liver metastasis via E-selectin-mediated extravasation and AKT signaling, suggesting it as a therapeutic target.

The paper investigates the genetic architecture of cortical expansion and regionalization by comparing genome-wide association studies of 24 cortical regions with and without adjustment for global measures, finding distinct genetic loci associated with different regions.

This paper quantifies structural connectome disruptions in glioblastoma patients using diffusion MRI and shows their association with worse prognosis and survival.

The paper uses MOSTest to analyze cortical morphology in 10,145 children, showing that regional cortical patterns predict cognitive performance after accounting for global brain measures.

The paper shows that distinct cortical morphology patterns are associated with different cognitive domains in children, highlighting the importance of sociodemographic factors.

The paper quantifies low perfusion compartments in glioblastoma using MRI and correlates them with patient survival outcomes.

This study uses joint histogram analysis of diffusion tensor imaging to identify tumor infiltration patterns in glioblastoma and their prognostic significance.