BioinformaticsbioRxivPreprint
Learning interpretable representation for context-specific transcription regulatory networks using a foundation model
Zhaowei Yu, Dongxu Yang, Qianqian Chen…·Yong Zhang
ChromBERT, a foundation model pre-trained on ChIP-seq data, generates interpretable representations of context-specific transcription regulatory networks and improves imputation and modeling of regulatory effects in cell types.