Author

Marco Troisi

Toscana Life SciencesORCID 0000-0002-4763-9886Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:bacteria (other)· 1 Approach:deep learning· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Ida PacielloiD· 2 shared Rino RappuoliiD· 2 shared Anna KabanovaiD· 1 shared Annalisa CiabattiniiD· 1 shared Cesira GiordanoiD· 1 shared Chiara Mugnaini· 1 shared Claudia SalaiD· 1 shared Concetta CastillettiiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersMicrobiology

Ida PacielloORCID

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2 papers

Recent·Most cited

Antigen-agnostic identification of poxvirus broadly neutralizing antibodies targeting OPG153

Ida Paciello, Ling Zhou, Emily J. Rundlet, Giulia Realini, Federica Perrone, Giulio Pierleoni, Marco Troisi, Jeanne Postal, Florence Guivel‐Benhassine, Françoise Porrot, Connor M. Mullins, Davide Moschese, Maria Vittoria Cossu, Federico Sabaini, Silvia Accordini, , Emanuele Andreano

The paper identifies OPG153 as a target of broadly neutralizing antibodies against MPXV and related viruses using antigen-agnostic isolation, AlphaFold 3 modeling, and cryo-EM.

Science Translational Medicine · Dec 10, 2025Peer-reviewedMicrobiology

Anti-capsule human monoclonal antibodies protect against hypervirulent and pandrug-resistant Klebsiella pneumoniae

Emanuele Roscioli, Vittoria Zucconi Galli Fonseca, Soraya Soledad Bosch, Ida Paciello, Giuseppe Maccari, Giulia Cardinali, Giampiero Batani, Samuele Stazzoni, Giusy Tiseo, Cesira Giordano, Yuwei Shen, Laura Capoccia, Dario Cardamone, Matteo Ridelfi, Marco Troisi, , Rino Rappuoli

This study isolates human monoclonal antibodies against hypervirulent, pandrug-resistant Klebsiella pneumoniae and identifies capsule-specific antibodies as protective against bloodstream infection.

Nature · Oct 1, 2025Peer-reviewedMicrobiology