Rino Rappuoli

This study isolates and characterizes monoclonal antibodies against Toscana virus's Gc glycoprotein, identifying cross-reactive antibodies that protect against Rift Valley Fever Virus.

The paper identifies OPG153 as a target of broadly neutralizing antibodies against MPXV and related viruses using antigen-agnostic isolation, AlphaFold 3 modeling, and cryo-EM.

This study isolates human monoclonal antibodies against hypervirulent, pandrug-resistant Klebsiella pneumoniae and identifies capsule-specific antibodies as protective against bloodstream infection.

The paper identifies a pan-betacoronavirus antibody that binds the S2 subunit of spike proteins and induces Fc-dependent antiviral responses, offering insights into non-neutralizing antibody protection.

The paper analyzes neutralizing antibodies from vaccinated and hybrid immune individuals to show that restored B cell germlines enhance neutralization against SARS-CoV-2 variants like BA.2.86.