Author

Aimin Zhou

East China Normal UniversityORCID 0000-0002-4768-5946Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Guixu ZhangiD· 1 shared Jingshan SheniD· 1 shared Qian ZhangiD· 1 shared Weiliang ZhuiD· 1 shared Wenhai YiniD· 1 shared Xiangrui JiangiD· 1 shared Xinyao CheniD· 1 shared Yan Zhang· 1 shared

Activity by Year

2024-2024 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperBioinformatics

Guixu ZhangORCID

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1 paper

Recent·Most cited

F-CPI: Prediction of activity changes induced by fluorine substitution using multimodal deep learning

Qian Zhang, Wenhai Yin, Xinyao Chen, Aimin Zhou, Guixu Zhang, Zhi Qing Zhao, Zhiqiang Li, Yan Zhang, Jingshan Shen, Weiliang Zhu, Xiangrui Jiang, Zhijian Xu

This study introduces F-CPI, a deep learning model to predict activity changes from fluorine substitution in drugs, achieving 89% accuracy and demonstrating its utility in optimizing SARS-CoV-2 3CLpro inhibitors.

bioRxiv · Jul 17, 2024 · PreprintBioinformatics