Xinyao Chen

This study identifies ADAMTSL4 as a causative gene for ectopia lentis et pupillae, showing its role in regulating extracellular matrix and cell migration through COL8A1.

This study develops a single-molecule technique to investigate cytoplasmic tail dynamics of membrane receptors in living cells, revealing ligand-induced activation mechanisms of β2AR.

This study introduces F-CPI, a deep learning model to predict activity changes from fluorine substitution in drugs, achieving 89% accuracy and demonstrating its utility in optimizing SARS-CoV-2 3CLpro inhibitors.