α-synuclein expression in response to bacterial ligands and metabolites in gut enteroendocrine cells
Michael J. Hurley, Elisa Menozzi, Sofia Koletsi, Rachel Bates, Matthew E. Gegg, Kai‐Yin Chau, Hervé M. Blottière, Jane Macnaughtan, Anthony H.V. Schapira
This study shows bacterial ligands and metabolites increase α-synuclein levels in gut enteroendocrine cells, potentially contributing to Parkinson's disease pathology.
Brain Communications · Jan 1, 2023Peer-reviewedNeuroscience