Long-read sequencing to interrogate strain-level variation among adherent-invasive Escherichia coli isolated from human intestinal tissue
Jeremy Wang, Rachel M. Bleich, Sandra Zarmer, Shiying Zhang, Belgin Dogan, Kenneth William Simpson, Janelle C. Arthur
The paper develops a long-read sequencing method to identify and distinguish AIEC strains in intestinal tissue, showing their ability to colonize IBD-susceptible mice and induce inflammation.
PLoS ONE · Oct 28, 2021Peer-reviewedGenomics