Kenneth William Simpson

Microfluidic cultivation enables probiotic growth under thermal stress

This study demonstrates a microfluidic platform that enables probiotic bacteria to grow under thermal stress by creating tailored thermal environments.

Genomic characterization of Escherichia coli harbor a polyketide synthase (pks) island associated with colorectal cancer (CRC) development

This study characterizes the genomic distribution and evolution of pks islands in E. coli strains associated with colorectal cancer, revealing phylogenetic patterns and horizontal gene transfer.

Long-read sequencing to interrogate strain-level variation among adherent-invasive Escherichia coli isolated from human intestinal tissue

The paper develops a long-read sequencing method to identify and distinguish AIEC strains in intestinal tissue, showing their ability to colonize IBD-susceptible mice and induce inflammation.

Imputation of canine genotype array data using 365 whole-genome sequences improves power of genome-wide association studies

The paper improves genome-wide association studies in dogs by imputing variants from 365 whole-genome sequences, increasing marker count 130-fold and enhancing power for complex trait mapping.