PathologybioRxiv
The Endothelium Modulates the Prothrombotic Phenotype of Factor V Leiden: Evidence from an Ex Vivo Model
Nadine Schwarz, Jens Müller, Hannah L. McRae…·Heiko Rühl
This study shows that endothelial cells from asymptomatic Factor V Leiden carriers have a higher APC response to thrombin formation compared to those with previous VTE, suggesting endothelial modulation of FVL's prothrombotic phenotype.
DOI 10.1161/atvbaha.124.322116