The Hidden Potential of PDE4 Inhibitor Rolipram: A Multifaceted Examination of its Inhibition of MMP2/9 Reveals Therapeutic Implications
Arka Bagchi, Analabha Roy, Anindya Halder, Arunima Biswas
This paper investigates rolipram's inhibition of MMP2/9 beyond its PDE4 activity, showing it affects MMP enzymatic activity and stability through direct protein binding.
Scientific Reports · Mar 31, 2025Peer-reviewedCancer Biology