Molecular BiologybioRxivPreprint
Myosin Light Chain Dephosphorylation by PPP1R12C Promotes Atrial Hypocontractility in Atrial Fibrillation
Srikanth Perike, Francisco J. González-González, Issam Abu-Taha…·Mark D. McCauley
This study shows PPP1R12C overexpression in AF patients and mice leads to MLC2a dephosphorylation, reduced atrial contractility, and increased AF inducibility.