Craig J. Goergen

This study examines how pregnancy affects cardiac function in mice with pre-existing hypertension, finding that pregnancy can mitigate some hypertension-related cardiac impairments.

NDC-1171, a SERCA pump modulator, preserves cardiac function in DMD mice but does not improve skeletal muscle function.

This study investigates the composition and structure of intraluminal thrombus in murine abdominal aortic aneurysms and its association with aneurysm expansion.

This paper introduces a refined murine model of reversible aortic constriction to study cardiac functional recovery, finding that while function recovers, structural and fibrotic changes persist.

This study uses high-resolution echocardiography in mice to track hemodynamic force metrics during pressure overload and recovery, finding systolic HDF ratios strongly correlate with cardiac dysfunction and recovery.

This study shows empagliflozin improves cardiac function and mitochondrial health in a mouse model of Duchenne muscular dystrophy.

This paper introduces a Bayesian framework using active membranes to infer skin biomechanical properties from strain fields without direct force measurements.

The paper investigates OPA1's role in cardiac function and metabolism using in silico and in vivo approaches, finding that OPA1 overexpression improves cardiac function and maintains metabolic markers in a mouse model.

This study shows that left atrial strain predicts cardiac dysfunction in a mouse model of pressure overload, with early detection before changes in volume or ejection fraction.

This paper introduces a method using low-dose isoproterenol to enhance cardiac dysfunction in mdx mice, showing increased myocyte injury, fibrosis, and reduced ventricular function compared to wild-type mice.

This study shows PPP1R12C overexpression in AF patients and mice leads to MLC2a dephosphorylation, reduced atrial contractility, and increased AF inducibility.