Author

Purnananda Guptasarma

Indian Institute of Science Education and Research MohaliORCID 0000-0002-4801-3180Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 2 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:E. coli· 2 Assay:proteomics· 2 Organism:bacteria (other)· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Archit GuptaiD· 2 shared Mehak Mahajan· 1 shared Saji Menon· 1 shared Snehal WaghmareiD· 1 shared Vikas YadaviD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

5 top collaborators · 4 mutual co-author links

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2 shared papersBiophysics

Archit GuptaORCID

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3 papers

Recent·Most cited

BiophysicsbioRxivPreprintAug 26, 2026

Stationary phase KCl levels trigger changes in Dps conformation to facilitate its partitioning between reversibly-aggregated deposits and Dps-DNA condensates

Mehak Mahajan, Archit Gupta, Purnananda Guptasarma

This study shows that stationary-phase KCl levels alter Dps conformation, enabling its reversible partitioning between LSPS aggregates and DNA condensates, facilitating DNA packaging during growth resumption.

DOI 10.64898/2026.08.21.746236

E. coliprotein structure

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BiochemistrybioRxivPreprintJan 19, 2026

Exploring differential interactional preferences of enzyme-bearing dockerins for cohesin domains in the Clostridium thermocellum cellulosome

Snehal Waghmare, Vikas Yadav, Saji Menon, Purnananda Guptasarma

The paper examines differential interactional preferences between cohesin and dockerin domains in the cellulosome of Clostridium thermocellum, identifying specific binding affinities and modes.

DOI 10.64898/2026.01.19.700288

bacteria (other)proteomics

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BiochemistryJournal of BacteriologyPeer-reviewedOct 24, 2024

E. coli cells advance into phase-separated (biofilm-simulating) extracellular polymeric substance containing DNA, HU, and lipopolysaccharide

Archit Gupta, Purnananda Guptasarma

The paper shows E. coli cells enter phase-separated extracellular polymeric substances containing HU, DNA, and LPS, with LPS modulating liquidity and structural integrity of biofilms.

4 citations

E. coliproteomics

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