Author

Sergei Sukharev

University of Maryland, College ParkORCID 0000-0002-4807-9665Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Organism:bacteria (other)· 1 Assay:electrophysiology· 1 Assay:fluorescence / live-cell microscopy· 1 Approach:simulation· 1 Approach:statistical model· 1

Frequent Co-Authors

Andriy AnishkiniD· 2 shared Christoph F. SchmidtiD· 1 shared Elissa MolleriD· 1 shared Hannah CetukiD· 1 shared Jake Rosetto· 1 shared Jeff D. EldredgeiD· 1 shared Octavio Albarrán· 1 shared Renata Garcés· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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Focal author (center)Selected co-authorORCID co-authorUnlinked name

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2 shared papersBiophysics

Andriy AnishkinORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

When do bacterial mechanosensitive channels get activated?

Sai Smaran, Octavio Albarrán, Renata Garcés, Jeff D. Eldredge, Sergei Sukharev, Christoph F. Schmidt

This study investigates when bacterial mechanosensitive channels activate by modeling stress distribution in the cell envelope during osmotic downshocks.

bioRxiv · Oct 24, 2026 · PreprintBiophysics

Desensitization, inactivation, and the tension-proof safety mechanism of inactivated MscS

Andriy Anishkin, Elissa Moller, Sergei Sukharev

This paper distinguishes between desensitization and inactivation of MscS channels using electrophysiology and simulations, showing inactivated channels resist activation under high tension.

Biophysical Journal · Jul 31, 2026Peer-reviewedBiophysics

Fluorescent peptides for membrane tension and domain structure reporting

Thomas M. Suchyna, Jake Rosetto, Hannah Cetuk, Andriy Anishkin, Sergei Sukharev

This paper introduces fluorescent peptide probes based on GsMTx4 to measure two-dimensional membrane tension and domain structure in biological membranes.

bioRxiv · Dec 31, 2025 · PreprintBiophysics