Christoph F. Schmidt

This study investigates when bacterial mechanosensitive channels activate by modeling stress distribution in the cell envelope during osmotic downshocks.

The paper shows that confined actomyosin networks generate self-centering steady-state flows that organize cellular debris into a central inclusion.

This study shows that cardiac sarcomeres exhibit stochastic heterogeneity and dynamic instability, which enable robust contraction despite mechanical constraints.

Myosin II in Drosophila cap cells pre-stretches proprioceptive chordotonal neurons, modulating their mechanical response and sensory adaptation.

The paper develops a continuum elastic model of E. coli peptidoglycan to study stress-strain relationships under large deformations and high turgor pressure.

SarcAsM provides a multiscale analysis tool for sarcomere structure and dynamics in cardiomyocytes using deep learning and graph-based methods.

DeepProjection extracts high-resolution content from 3D microscopy stacks by masking background, enabling dynamic tracking of tissue sheets in developmental biology.

The paper identifies DBN-1 as a regulator of body bending in C. elegans by suppressing NCA cation leak channels, leading to hyper-bending in mutants.