Prashant Kumar Modi

Systems level phosphoproteomics reveals CAMKK2 driven kinase signaling underlying malignant phenotypes in gastric cancer

This study identifies CAMKK2 as a key driver of kinase signaling in gastric cancer through phosphoproteomic analysis, showing its role in promoting proliferation and malignant traits.

Temporal phosphoproteomics reveals rapid restoration of kinase signaling by Glycyrrhiza glabra in a rotenone-induced Parkinson disease model

This study uses temporal phosphoproteomics to show Glycyrrhiza glabra restores kinase signaling in a rotenone-induced Parkinson's model, identifying key pathways involved in neuroprotection.

Integrated Metabolomic, Proteomic, and Phosphoproteomic Profiling Reveals CAMKK2-Dependent Regulation of Cell Cycle and Nucleotide Metabolism in Gastric Cancer

This study identifies CAMKK2 as a regulator of nucleotide metabolism and cell cycle in gastric cancer, showing its inhibition disrupts DNA replication and causes mitotic failure.

Phosphoproteomic profiling reveals signaling pathways modulated by Annona muricata leaf extract in oral adenosquamous carcinoma cells

This study uses phosphoproteomics to show that Annona muricata leaf extract inhibits oncogenic signaling in oral cancer cells by inducing hypophosphorylation of key pathways.

Serial enrichment based quantitative proteomics enables deep and multiplexed profiling of post-translational modifications

This paper introduces a serial enrichment workflow for quantitative proteomics that enables deep and multiplexed profiling of multiple post-translational modifications from a single sample.